CT Heart - CAM 712

GENERAL INFORMATION 

It is an expectation that all patients receive care/services from a licensed clinician. All appropriate supporting documentation, including recent pertinent office visit notes, laboratory data, and results of any special testing must be provided. If applicable: All prior relevant imaging results and the reason that alternative imaging cannot be performed must be included in the documentation submitted. 

Where a specific clinical indication is not directly addressed in this guideline, medical necessity determination will be made based on widely accepted standard of care  criteria. These criteria are supported by evidence-based or peer-reviewed sources such as medical literature, societal guidelines and state/national recommendations.

Policy
INDICATIONS FOR HEART COMPUTED TOMOGRAPHY (CT)1,2

Congenital Heart Disease3

For all indications below, either CT or CMR can be performed: 

  • All congenital lesions: prior to planned repair and for change in clinical status and/or new concerning signs or symptoms
  • Patent ductus arteriosus: routine surveillance (1 – 2 years) in a patient with postprocedural aortic obstruction
  • Aortic stenosis or regurgitation: routine surveillance (6 – 12 months) in a child with aortic sinus and/or ascending aortic dilation with increasing size
  • Aortic coarctation and interrupted aortic arch: 
    • Routine surveillance (3 .– 5 years) in a child or adult with mild aortic coarctation
    • Post procedure (surgical or catheter-based) routine surveillance (3 – 5 years) in an asymptomatic patient to evaluate for aortic arch aneurysms, in-stent stenosis, stent fracture, or endoleak
  • Tetralogy of Fallot: 
    • Routine surveillance (2 – 3 years) in a patient with valvular or ventricular dysfunction, right ventricular outflow tract obstruction, branch pulmonary artery stenosis, arrhythmias, or presence of an RV-to-PA conduit
  • D-Loop transposition of the great arteries (postoperative):
    • Routine surveillance (3 – 5 years) in an asymptomatic patient
    • Routine surveillance (1 – 2 years) in a patient with dilated aortic root with increasing size, or aortic regurgitation
    • Routine surveillance (3 – 12 months) in a patient with ≥ moderate systemic AV valve regurgitation, systemic RV dysfunction, LVOT obstruction, or arrhythmias
  • Congenitally corrected transposition of the great arteries:
    • Unrepaired: routine surveillance (3 – 5 years) in an asymptomatic patient
    • Postoperative: routine surveillance (3 – 5 years) in an asymptomatic patient
    • Postoperative anatomic repair: routine surveillance (6 – 12 months) in a patient with valvular or ventricular dysfunction, right or left ventricular outflow tract obstruction, or presence of an RV-to-PA conduit
    • Postoperative physiological repair with VSD closure and/or LV-to-PA conduit: routine surveillance (3 – 12 months) in a patient with ≥ moderate systemic AV valve regurgitation, systemic RV dysfunction, and/or LV-to-PA conduit dysfunction
  • Truncus arteriosus: routine surveillance (1 – 2 years) in an asymptomatic child or adult with ≥ moderate truncal stenosis and/or regurgitation 
  • Single-Ventricle Heart Disease (includes hypoplastic left heart syndrome, double-inlet LV, double-inlet RV, mitral atresia, tricuspid atresia, unbalanced A-V septal defect): postoperative routine surveillance (3 – 5 years) in an asymptomatic patient 

Cardiomyopathy

  • Quantification of myocardial (muscle) mass (CMR or CT)
  • Assessment of right ventricular morphology in suspected arrhythmogenic right ventricular cardiomyopathy, based upon other findings such as:
    • Nonsustained VT
    • Unexplained syncope
    • ECG abnormalities
    • First-degree relative with positive genotype of ARVC (either, but CMR is superior to CT)4,5

Valvular Heart Disease 

  • Characterization of native or prosthetic valves with clinical signs or symptoms suggesting valve dysfunction, when TTE, TEE, and/or fluoroscopy have been inadequate6
  • Evaluation of RV function in severe TR, including systolic and diastolic volumes, when TTE images are inadequate and CMR is not readily available
  • Pulmonary hypertension in the absence of severe valvular disease
  • Evaluation of suspected infective endocarditis with moderate to high pretest probability (i.e., staph bacteremia, fungemia, prosthetic heart valve, or intracardiac device), when 
  • TTE and TEE have been inadequate
  • Evaluation of suspected paravalvular infections when the anatomy cannot be clearly delineated by TTE and TEE7

Evaluation of Intra- and Extra-Cardiac Structures

  • Evaluation of cardiac mass, suspected tumor or thrombus, or cardiac source of emboli, when imaging with TTE and TEE have been inadequate 
  • Re-evaluation of prior findings for interval change (i.e., reduction or resolution of atrial thrombus after anticoagulation), when a change in therapy is anticipated6,7,8
  • Evaluation of pericardial anatomy, when TTE and/or TEE are inadequate or for better tissue characterization of a mass and detection of metastasis [CMR superior for physiologic assessment (constrictive versus restrictive) and tissue characterization, CT superior for calcium assessment]9,10

Electrophysiologic Procedure Planning2

  • Evaluation of pulmonary venous anatomy prior to radiofrequency ablation of atrial fibrillation and for follow-up when needed for evaluation of pulmonary vein stenosis 
  • Non-invasive coronary vein mapping prior to placement of biventricular pacing leads

Transcatheter Structural Intervention Planning

  • Evaluation for transcatheter aortic valve replacement (TAVR)6,11,12
  • When TTE and TEE cannot provide adequate imaging, CT imaging can be used for planning: robotic mitral valve repair, atrial septal defect closure, left atrial appendage closure, ventricular septal defect closure, endovascular grafts, and percutaneous pulmonic valve implantation12,13
  • Evaluation for suitability of transcatheter mitral valve procedures, alone or in addition to TEE14

Aortic Pathology6,7,8,15,16,17,18,19,20,21

  • CT, MR, or echo can be used for screening and follow-up, with CT and MR preferred for imaging beyond the proximal ascending thoracic aorta in the following scenarios:
    • Evaluation of dilated aortic sinuses or ascending aorta identified by TTE
    • Suspected acute aortic pathology, such as dissection
    • Re-evaluation of known aortic dilation or aortic dissection with a change in clinical status or cardiac examination or when findings would alter management 
    • Screening first-degree relatives of individuals with a history of thoracic aortic aneurysm or dissection, or an associated high-risk mutation for thoracic aneurysm in common
    • Screening second-degree relative of a patient with thoracic aortic aneurysm, when the first-degree relative has aortic dilation, aneurysm, or dissection
    • Six-month follow-up after initial finding of a dilated thoracic aorta, for assessment of rate of change 
    • Annual follow-up of enlarged thoracic aorta with size up to 4.4 cm 
    • Biannual (twice/yr) follow-up of enlarged aortic root ≥ 4.5 cm or showing growth rate ≥ 0.5 cm/year
  • Patients with Marfan syndrome may undergo annual imaging with CT, MRI or TTE, with increase to biannual (twice-yearly) when diameter ≥ 4.5 cm or when expansions is > 0.5 cm/yr 
  • Patient with Turner syndrome should undergo initial imaging with CT, MRI, or TTE for evidence of dilatation of the ascending thoracic aorta. If imaging is normal and there areno risk factors for aortic dissection, repeat imaging should be performed every 5 - 10 years, or if otherwise indicated. If the aorta is enlarged, appropriate follow-up imaging should be done according to size, as above
  • Evaluation of the aorta in the setting of a known or suspected connective tissue disease or genetic condition that predisposes to aortic aneurysm or dissection (i.e., Loeys-Dietz, Ehlers-Danlos), with re-evaluation at 6 months for rate of expansion. Complete evaluation with CMR from the cerebrovascular circulation to the pelvis is recommended with Loeys-Dietz syndrome.

Rationale

  • Cardiac computed tomography (Heart CT) images the cardiac chambers, great vessels, valves, myocardium, and pericardium to assess cardiac structure and  function, particularly when echocardiography (transthoracic echocardiography and transesophageal echocardiography) cannot provide adequate information
  • CT imaging can be used for assessment of: 
    • Structures of the heart (e.g., chambers, valves, great vessels, masses), as in this guideline
    • Quantitative level of calcium in the walls of the coronary arteries, in the separate coronary artery calcium (CAC) scoring guideline

OVERVIEW2
Imaging in Congenital Heart Disease

Echocardiography is often utilized for initial assessment of congenital heart disease. However, if findings are unclear or need confirmation, CMR or CT can be useful.3

CT and Cardiac Masses
CT and CMR are used to evaluate cardiac masses, describing their size, density, tissue characteristics, and spatial relationship to adjacent structures. 

CT and Pericardial Disease
While echocardiography is most often used in the initial examination of pericardial disease, CT and CMR can evaluate pericardial thickening and masses which are often detected initially with echocardiography. CT and CMR can accurately define the site and extent of masses, e.g., cysts, hematomas, and neoplasms.9  

Abbreviations

ARVD/C Arrhythmogenic right ventricular dysplasia/cardiomyopathy
CABG Coronary artery bypass grafting surgery
CAD Coronary artery disease
CCS Coronary calcium score
CCT Cardiac (heart) CT
CHD Coronary heart disease
CMR Cardiac magnetic resonance (imaging)
CT Computed tomography
CTA Computed tomography angiography
ECG Electrocardiogram
EF Ejection fraction
HF Heart failure
LVOT Left ventricular outflow tract
MI Myocardial infarction
MPI Myocardial perfusion Imaging or cardiac nuclear imaging
MR(I) Magnetic resonance (imaging)
PA Pulmonary artery
PCI Percutaneous coronary intervention
PVML Paravalvular mitral leak
RV Right ventricle
SE Stress echocardiogram
TAVR Transcatheter aortic valve replacement
TMVR Transcatheter mitral valve replacement
TR Tricuspid regurgitation
TEE Transesophageal echocardiography
TTE Transthoracic echocardiography
VT Ventricular tachycardia

References

  1. Douglas PS, Garcia MJ, Haines DE, et al. ACCF/ASE/AHA/ASNC/HFSA/HRS/SCAI/SCCM/SCCT/SCMR 2011 Appropriate Use Criteria for Echocardiography. A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, American Society of Echocardiography, American Heart Association, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Critical Care Medicine, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance Endorsed by the American College of Chest Physicians. J Am Coll Cardiol. Mar 1 2011;57(9):1126-66. doi:10.1016/j.jacc.2010.11.002
  2. Taylor AJ, Cerqueira M, Hodgson JM, et al. ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 appropriate use criteria for cardiac computed tomography. A report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the Society of Cardiovascular Computed Tomography, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the American Society of Nuclear Cardiology, the North American Society for Cardiovascular Imaging, the Society for Cardiovascular Angiography and Interventions, and the Society for Cardiovascular Magnetic Resonance. J Am Coll Cardiol. Nov 23 2010;56(22):1864-94. doi:10.1016/j.jacc.2010.07.005
  3. Sachdeva R, Valente AM, Armstrong AK, et al. ACC/AHA/ASE/HRS/ISACHD/SCAI/SCCT/SCMR/SOPE 2020 Appropriate Use Criteria for Multimodality Imaging During the Follow-Up Care of Patients With Congenital Heart Disease: A Report of the American College of Cardiology Solution Set Oversight Committee and Appropriate Use Criteria Task Force, American Heart Association, American Society of Echocardiography, Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Pediatric Echocardiography. J Am Coll Cardiol. Feb 18 2020;75(6):657-703. doi:10.1016/j.jacc.2019.10.002
  4. Marcus FI, McKenna WJ, Sherrill D, et al. Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria. Circulation. Apr 6 2010;121(13):1533-41. doi:10.1161/circulationaha.108.840827
  5. Te Riele A, Tandri H, Sanborn DM, Bluemke DA. Noninvasive Multimodality Imaging in ARVD/C. JACC Cardiovasc Imaging. May 2015;8(5):597-611. doi:10.1016/j.jcmg.2015.02.007
  6. Doherty JU, Kort S, Mehran R, Schoenhagen P, Soman P. ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2017 Appropriate Use Criteria for Multimodality Imaging in Valvular Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. J Am Coll Cardiol. Sep 26  2017;70(13):1647-1672. doi:10.1016/j.jacc.2017.07.732
  7. Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. Jun 10 2014;63(22):e57-185. doi:10.1016/j.jacc.2014.02.536
  8. Baumgartner H, Falk V, Bax JJ, et al. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J. Sep 21 2017;38(36):2739-2791. doi:10.1093/eurheartj/ehx391
  9. Klein AL, Abbara S, Agler DA, et al. American Society of Echocardiography clinical recommendations for multimodality cardiovascular imaging of patients with pericardial disease: endorsed by the Society for Cardiovascular Magnetic Resonance and Society of Cardiovascular Computed Tomography. J Am Soc Echocardiogr. Sep 2013;26(9):965-1012.e15. doi:10.1016/j.echo.2013.06.023
  10. Pennell DJ. Cardiovascular magnetic resonance. Circulation. Feb 9 2010;121(5):692-705. doi:10.1161/circulationaha.108.811547
  11. Otto CM, Kumbhani DJ, Alexander KP, et al. 2017 ACC Expert Consensus Decision Pathway for Transcatheter Aortic Valve Replacement in the Management of Adults With Aortic Stenosis: A Report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol. Mar 14 2017;69(10):1313-1346. doi:10.1016/j.jacc.2016.12.006 
  12. Schoenhagen P, Numburi U, Halliburton SS, et al. Three-dimensional imaging in the context of minimally invasive and transcatheter cardiovascular interventions using multi-detector computed tomography: from pre-operative planning to intra-operative guidance. Eur Heart J. Nov 2010;31(22):2727-40. doi:10.1093/eurheartj/ehq302
  13. Pison L, Potpara TS, Chen J, Larsen TB, Bongiorni MG, Blomström-Lundqvist C. Left atrial appendage closure-indications, techniques, and outcomes: results of the European Heart Rhythm Association Survey. Europace. Apr 2015;17(4):642-6. doi:10.1093/europace/euv069 
  14. Wunderlich NC, Beigel R, Ho SY, et al. Imaging for Mitral Interventions: Methods and Efficacy. JACC Cardiovasc Imaging. Jun 2018;11(6):872-901. doi:10.1016/j.jcmg.2018.02.024
  15. Doherty JU, Kort S, Mehran R, et al. ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2019 Appropriate Use Criteria for Multimodality Imaging in the Assessment of Cardiac Structure and Function in Nonvalvular Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and the Society of Thoracic Surgeons. J Am Coll Cardiol. Feb 5 2019;73(4):488-516. doi:10.1016/j.jacc.2018.10.038
  16. Bhave NM, Nienaber CA, Clough RE, Eagle KA. Multimodality Imaging of Thoracic Aortic Diseases in Adults. JACC Cardiovasc Imaging. Jun 2018;11(6):902-919. doi:10.1016/j.jcmg.2018.03.009
  17. Erbel R, Aboyans V, Boileau C, et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC). Eur Heart J. Nov 1 2014;35(41):2873-926. doi:10.1093/eurheartj/ehu281
  18. Hendel RC, Patel MR, Kramer CM, et al. ACCF/ACR/SCCT/SCMR/ASNC/NASCI/SCAI/SIR 2006 appropriateness criteria for cardiac computed tomography and cardiac magnetic resonance imaging: a report of the American College of Cardiology Foundation Quality Strategic Directions Committee Appropriateness Criteria Working Group, American College of Radiology, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, American Society of Nuclear Cardiology, North American Society for Cardiac Imaging, Society for Cardiovascular Angiography and Interventions, and Society of Interventional Radiology. J Am Coll Cardiol. Oct 3 2006;48(7):1475-97. doi:10.1016/j.jacc.2006.07.003
  19. Hiratzka LF, Bakris GL, Beckman JA, et al. 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with Thoracic Aortic Disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. Circulation. Apr 6 2010;121(13):e266-369. doi:10.1161/CIR.0b013e3181d4739e
  20. Svensson LG, Adams DH, Bonow RO, et al. Aortic valve and ascending aorta guidelines for management and quality measures. Ann Thorac Surg. Jun 2013;95(6 Suppl):S1-66. doi:10.1016/j.athoracsur.2013.01.083
  21. Isselbacher EM, Preventza O, Hamilton Black J, 3rd, et al. 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. Dec 13 2022;146(24):e334-e482. doi:10.1161/cir.0000000000001106

Coding Section

Codes

Number

Description

CPT

75572

Computed tomography, heart, with contrast material, for evaluation of cardiac structure and morphology (including 3D image postprocessing, assessment of cardiac function, and evaluation of venous structures, if performed)

 

75573

Computed tomography, heart, with contrast material, for evaluation of cardiac structure and morphology in the setting of congenital heart disease (including 3D image postprocessing, assessment of LV cardiac function, RV structure and function and evaluation of venous structures, if performed)

Procedure and diagnosis codes on Medical Policy documents are included only as a general reference tool for each policy. They may not be all-inclusive. 

This medical policy was developed through consideration of peer-reviewed medical literature generally recognized by the relevant medical community, U.S. FDA approval status, nationally accepted standards of medical practice and accepted standards of medical practice in this community, Blue Cross Blue Shield Association technology assessment program (TEC) and other nonaffiliated technology evaluation centers, reference to federal regulations, other plan medical policies, and accredited national guidelines.

"Current Procedural Terminology © American Medical Association. All Rights Reserved" 

History From 2019 Forward 

12/01/2023 Annual review, no change to policy intent. Entire policy updated for consistency.
12/07/2022 Annual review, multiple changes to coverage criteria.
12/08/2021  Annual review, no change to intent. Reorganizing description 
11/12/2020  Annual review, revising criteria for congenital heart disease, adding verbiage for infective endocarditis. Also updating description and references. 
12/6/2019               NEW POLICY     
Complementary Content
${loading}