GENERAL INFORMATION 
It is an expectation that all patients receive care/services from a licensed clinician. All appropriate supporting documentation, including recent pertinent office visit notes, laboratory data, and results of any special testing must be provided. If applicable: All prior relevant imaging results and the reason that alternative imaging cannot be performed must be included in the documentation submitted.

Policy
INDICATIONS FOR LUMBAR SPINE SURGERY1
Lumbar Discectomy/Microdiscectomy: Surgical indications for inter-vertebral disc herniation*

• When ALL of the following are present:
  • Primary radicular symptoms noted upon clinical exam that significantly hinders daily activities^2-7 
  • Failure to improve with at least 6 consecutive weeks in the last 6 months of documented, physician directed appropriate conservative treatment to include at least 2 of the following^{3, 7, 8}: 
    • Analgesics, steroids, and/or NSAIDs
    • Structured program of physical therapy
    • Structured home exercise program prescribed by a physical therapist, chiropractic provider or physician 
    • Epidural steroid injections and or selective nerve root block AND
  • Imaging studies showing evidence of inter-vertebral disc herniation that correlate exactly with the individual’s symptoms/signs^{3, 7, 9, 10} OR

*Other Indications: Microdiscectomy may be used as the first line of treatment (no conservative treatment required) in the following clinical scenarios3:

• Progressive nerve compression resulting in an acute neurologic deficit (motor) due to herniated disc. The neurological deficits should be significant: 0-2/5 on the motor function scale for L5 or S1 roots OR 0-3/5 for L3 or L4 roots. Lesser degrees of motor dysfunction may resolve with conservative treatment and are not considered an indication for early surgery OR
• Cauda equina syndrome (loss of bowel or bladder control)

NOTE: Percutaneous lumbar discectomy, radiofrequency disc decompression, and related procedures are deemed investigational procedures and are not approved. Discectomy and microdiscectomy are the gold standards.

Lumbar Decompression: Laminectomy, Laminotomy, Facetectomy, and Foraminotomy. 
These procedures allow decompression by partial or total removal of various parts of vertebral bone and ligaments. Surgical indications for spinal canal decompression due to lumbar spinal stenosis*:

• When ALL of the following are present:
  • Neurogenic claudication, and/or radicular leg pain that impairs daily activities^{2-7, 9-14}
  • Failure to improve with at least 6 consecutive weeks in the last 6 months of documented, physician directed appropriate conservative therapy to include at least two (2) of the following^{3, 8}:
    • Analgesics, steroids, and/or NSAIDs
    • Structured program of physical therapy 
    • Structured home exercise program prescribed by a physical therapist, chiropractic provider or physician 
    • Epidural steroid injections and or selective nerve root block
  • Imaging findings demonstrating moderate to severe stenosis consistent with clinical signs/symptoms^{3, 13, 14} OR

*Other Indications: Lumbar decompression may be used as the first line of treatment (no conservative treatment required) in any of the following clinical scenarios^{3, 7}:

• Progressive nerve compression resulting in an acute neurologic (motor) deficit. The neurological deficits should be significant: 0-2/5 on the motor function scale for L5 or S1 roots OR 0-3/5 for L3 or L4 roots. Lesser degrees of motor dysfunction may resolve with conservative treatment and are not considered an indication for early surgery OR
• Cauda equina syndrome (loss of bowel or bladder control) OR
• Spinal stenosis due to tumor, infection, or trauma

NOTE: Percutaneous decompressions, endoscopic decompression, and related procedures (laser, etc.) are deemed investigational procedures and are not approved. Open or microdecompression via laminectomy or laminotomy are the gold standards.^{3, 7}

Lumbar Spine Fusion
Single Level Fusion with or without Decompression
Because of variable outcomes with fusion surgery, individuals should be actively involved in the decision-making process and provided appropriate decision-support materials explaining potential risks/benefits and treatment alternatives when considering this intervention. 

• When ALL of the following are present*:
  • Lumbar back pain, neurogenic claudication, and/or radicular leg pain without sensory or motor deficit that impairs daily activities for at least 6 months^{2-7, 12, 13, 15-22}
  • Failure to improve with at least 6 consecutive weeks in the last 6 months of documented, physician directed appropriate conservative therapy (6 months for isolated low back pain to include at least two (2) of the following^{2, 3, 5, 7, 8, 15, 18-21}:
    • Analgesics, steroids, and/or NSAIDs
    • Structured program of physical therapy 
    • Structured home exercise program prescribed by a physical therapist, chiropractic provider or physician 
    • Epidural steroid injections and or facet injections/selective nerve root block
  • Imaging studies corresponding to the clinical findings^{3, 13-15, 18, 19, 21}
  • At least ONE of the following clinical conditions: 
    • Spondylolisthesis (neural arch defect - spondylolytic spondylolisthesis, degenerative spondylolisthesis, and congenital unilateral neural arch hypoplasia)^{13, 18, 19, 21-25}
    • Evidence of segmental instability - Excessive motion, as in degenerative spondylolisthesis, segmental instability, and surgically induced segmental instability^{13, 18, 19, 21-25}
    • Revision surgery for failed previous operation(s) for pseudoarthrosis at the same level at least 6-12 months from prior surgery** if significant functional gains are anticipated²⁶
    • Revision surgery for failed previous operation(s) repeat disk herniations if significant functional gains are anticipated (Note: Many recurrent disc herniations can be treated with discectomy alone, so specific indications for the addition of fusion will be required)³
    • Fusion for the treatment of spinal tumor, cancer, or infection²⁶
    • Chronic low back pain or degenerative disc disease (disc degeneration without significant neurological compression presenting with low back pain) must have failed at least 6 months of appropriate active non-operative treatment (completion of a comprehensive cognitive -behavioral rehabilitation program is mandatory) and must be evaluated on a case-by-case basis^{2, 5, 7, 9, 10, 16, 17, 20, 23, 25} 

NOTE: The results of several randomized trials suggests that in many degenerative cases un-instrumented posterolateral intertransverse fusion has similar results to larger instrumented (PLIF, TLIF, etc.) fusion techniques with fewer morbidities and less likelihood of revision surgery. Accordingly, specific findings suggesting more significant instability should be present when larger techniques are used (gaping of facets, gross motion on flexion/extension radiographs, wide disc spaces)^{22, 23, 25, 27-29} OR 

*Other Indications: Lumbar spinal fusion may be used as the first line of treatment (no conservative treatment required) in the following clinical scenarios^{3, 7}:

• Progressive nerve compression resulting in an acute neurologic deficit (motor) AND 
  • One of the aforementioned clinical conditions, except chronic low back pain or degenerative disc disease. The neurological deficits must be significant: 0-2/5 on the motor function scale for L5 or S1 roots OR 0-3/5 for L3 or L4 roots. Lesser degrees of motor dysfunction may resolve with conservative treatment and are not considered an indication for early surgery. 
• Cauda equina syndrome (loss of bowel or bladder control) AND 
  • One of the aforementioned clinical conditions, except chronic low back pain or degenerative disc disease.

** REPEAT LUMBAR SPINE FUSION OPERATIONS: Repeat lumbar fusion operations will be reviewed on a case-by-case basis upon submission of medical records and imaging studies that demonstrate remediable pathology. The below must also be documented and available for review of repeat fusion requests^{2, 5, 7, 17, 20, 23, 25}: 
o Rationale as to why surgery is preferred over other non-invasive or less invasive treatment procedures
o Signed documentation that the individual has participated in the decision-making process and understands the high rate of failure/complications

Multi-level Fusion with or without decompression (all multi-level fusion surgeries will be reviewed on a case-by-case basis): 
Because of variable outcomes with fusion surgery, individuals should be actively involved in the decision-making process and provided appropriate decision-support materials explaining potential risks/benefits and treatment alternatives when considering this intervention. 

• When ALL of the following are present*:
  • Lumbar back pain, neurogenic claudication, and/or radicular leg pain without sensory or motor deficit that impairs daily activities for at least 6 months^{2, 4-7, 12, 13, 16, 17, 20}
  • Failure to improve with at least 6 consecutive weeks in the last 6 months of documented, physician directed appropriate conservative therapy to include at least two (2) of the following^{8, 18-21}:
    • Analgesics, steroids, and/or NSAIDs
    • Structured program of physical therapy 
    • Structured home exercise program prescribed by a physical therapist, chiropractic provider or physician 
    • Epidural steroid injections and or facet injections/selective nerve root block
  • Imaging studies corresponding to the clinical findings^{3, 13-15, 18, 19, 21}
  • At least ONE of the following clinical conditions^{18, 19, 21-25}:
    • Multiple level spondylolisthesis (Note: Fusions in cases with single level spondylolisthesis should be limited to the unstable level)
    • Fusion for the treatment of spinal tumor, trauma, cancer, or infection affecting multiple levels 
    • Intra-operative segmental instability OR 

*Other Indications: Lumbar spinal fusion may be used as the first line of treatment (no conservative treatment required) in the following clinical scenarios^{3, 7}:

• Progressive nerve compression resulting in an acute neurologic deficit (motor) AND
  • One of the aforementioned clinical conditions except chronic low back pain or degenerative disc disease. The neurological deficits must be significant: 0-2/5 on the motor function scale for L5 or S1 roots OR 0-3/5 for L3 or L4 roots. Lesser degrees of motor dysfunction may resolve with appropriate conservative treatment and are not considered an indication for early surgery OR 
• Cauda equina syndrome (loss of bowel or bladder control) AND
  • One of the aforementioned clinical conditions, except chronic low back pain or degenerative disc disease.

NOTE: Instrumentation, bone formation or grafting materials, including biologics, should be used at the surgeon’s discretion; however, use should be limited to FDA approved indications regarding the specific devices or biologics.

NOTE: This lumbar surgery guideline does not address spinal deformity surgeries or the clinical indications for spinal deformity surgery.

NOTE: Pre-sacral, axial lumbar interbody fusion (AxiaLIF) is not an approved surgical approach due to insufficient evidence. 

RELATIVE CONTRAINDICATIONS FOR SPINE SURGERY (NOTE: Cases may not be approved if the below contraindications exist):

• Medical contraindications to surgery (e.g., severe osteoporosis; infection of soft tissue adjacent to the spine and may be at risk for spreading to the spine; severe cardiopulmonary disease; anemia; malnutrition and systemic infection).^{30, 31}
• Psychosocial risk factors. It is imperative to rule out non-physiologic modifiers of pain presentation or non-operative conditions mimicking radiculopathy or instability (e.g., 
• peripheral neuropathy, piriformis syndrome, myofascial pain, sympathetically mediated pain syndromes, sacroiliac dysfunction, psychological conditions, etc.) prior to consideration of elective surgical intervention.^{3, 7} Individuals with clinically significant depression or other psychiatric disorders being considered for elective spine surgery will be reviewed on a case-by-case basis and the surgery may be denied for risk of failure. 
• Active Tobacco or Nicotine use prior to fusion surgery. Individuals must be free from smoking and/or nicotine use for at least six weeks prior to surgery and during the entire period of fusion healing.^32-37
• Morbid Obesity. Contraindication to surgery in cases where there is significant risk and concern for improper post-operative healing, post-operative complications related to morbid obesity, and/or an inability to participate in post-operative rehabilitation.38 These cases will be reviewed on a case-by-case basis and may be denied given the risk of failure.

Rationale
Lumbar Discectomy/Microdiscectomy is a surgical procedure to remove part of the damaged spinal disc. The damaged spinal disc herniates into the spinal canal and compresses the nerve roots. Nerve root compression leads to symptoms like low back pain, radicular pain, numbness and tingling, muscular weakness, and paresthesia. Typical disc herniation pain is exacerbated with any movement that causes the disc to increase pressure on the nerve roots. 

Lumbar Decompression (Laminectomy, Laminotomy, Facetectomy, and Foraminotomy): Laminectomy is a common decompression surgery. The American Association of Neurological Surgeons defines laminectomy as a surgery to remove the back part of vertebra, lamina, to create more space for the spinal cord and nerves. The most common indication for laminectomy is spinal stenosis. Spondylolisthesis and herniated disk are also frequent indications for laminectomy. Decompression surgery is usually performed as part of lumbar fusion surgery. 

Lumbar Fusion Surgery: Lumbar spinal fusion (arthrodesis) is a surgical procedure used to treat spinal conditions of the lumbar, e.g., degenerative disc disease, spinal stenosis, injuries/fractures of the spine, spinal instability, and spondylolisthesis. Spinal fusion is a “welding” process that permanently fuses or joins together two or more adjacent bones in the spine, immobilizing the vertebrae and restricting motion at a painful joint. It is usually performed after other surgical procedures of the spine, such as discectomy or laminectomy. The goal of fusion is to increase spinal stability, reduce irritation of the affected nerve roots, compression on the spinal cord, disability, and 
pain and/or numbness. Clinical criteria for single level fusion versus multiple level fusions are outlined under the indications section.

OVERVIEW
This guideline outlines the key surgical treatments and indications for common lumbar spinal disorders and is a consensus document based upon the best available evidence. Spine surgery is a complex area of medicine, and this document breaks out the treatment modalities for lumbar spine disorders into surgical categories: lumbar discectomy/microdiscectomy, lumbar decompression,and lumbar fusion surgery. See below for procedures considered NOT MEDICALLY NECESSARY.

• Spinal surgeries should be performed only by those with extensive surgical training (neurosurgery, orthopedic surgery)
• Services Not Covered: The following procedures are considered either still under investigation or are not recommended based upon the current evidence: Percutaneous lumbar discectomy; Laser discectomy; percutaneous radiofrequency disc decompression; intradiscal electrothermal annuloplasty (IDEA) or more commonly called IDET (intradiscal electrothermal therapy); nucleus pulpous replacement; and pre-sacral fusion.
  • PERCUTANEOUS DISCECTOMY is an invasive operative procedure to accomplish partial removal of the disc through a needle which allows aspiration of a portion of the disc under imaging control. Its only indication is to obtain diagnostic tissue, such as, for a biopsy for discitis. Its effectiveness has not been fully established.
  • LASER DISCECTOMY is a procedure which involves the delivery of laser energy into the center of the nucleus pulposus using a fluoroscopically guided laser fiber under local anesthesia. The energy denatures protein in the nucleus, causing a structural change which is intended to reduce intradiscal pressure. Its effectiveness has not been fully established.
  • INTRADISCAL ELECTROTHERMAL ANNULOPLASTY (IDEA) (more commonly called IDET, or Intradiscal Electrothermal therapy) is an outpatient non-operative procedure in which a wire is guided into the identified painful disc using fluoroscopy. The wire is then heated at the nuclear-annular junction within the disc. It has not been shown to be effective.
  • NUCLEUS PULPOSUS REPLACEMENT Involves the introduction of a prosthetic implant into the intervertebral disc, replacing the nucleus pulposus while preserving the annulus fibrosus. It has not been shown to be effective relative to other gold standard interventions.
• Conservative Therapy: (Musculoskeletal) includes primarily physical therapy and/or injections; and a combination of modalities, such as rest, ice, heat, modified activities, medical devices (such as braces), medications, diathermy, chiropractic treatments, or physician supervised home exercise program. 
• Home Exercise Program - (HEP) – the following two elements are required to meet guidelines for completion of conservative therapy: 
  • Documentation provided of an exercise prescription/plan AND
  • Follow up with member with information provided regarding completion of HEP (after suitable 4–6-week period) or inability to complete HEP due to physical reason- i.e., increased pain, inability to physically perform exercises. (Inconvenience or noncompliance without explanation does not constitute “inability to complete” HEP). 
• Isolated Low Back Pain - Pain isolated to the lumbar region of the spine and the surrounding paraspinal musculature. Also referred to ‘mechanical low back pain’ or ‘discogenic pain’. No associated neurogenic claudication or radiculopathy.
• Lumbar Fusion - Fusions can be performed either anteriorly, laterally, or posteriorly, or via a combined approach, although simple posterolateral fusions are indicated in the great majority of cases requiring fusion. Aggressive surgical approaches to fusion may be an indication for denial of cases (when such techniques have not been demonstrated to be superior to less morbid techniques) or recommendation for alternative procedure. These are the surgical approaches:
  • Intertransverse fusion or posterolateral fusion
  • Anterior interbody fusion (ALIF) 
  • Lateral or transpsoas interbody fusion (XLIF) 
  • Posterior or trans-foraminal interbody fusion (PLIF or TLIF)
  • Anterior/posterior fusion (360-degree) 
  • Pre-sacral, axial lumbar interbody fusion (AxiaLIF) is still being investigated and is not recommended.
    • Use of bone grafts including autologous or allograft which might be combined with metal or biocompatible devices to produce a rigid, bony connection between two or more adjacent vertebrae are common. Bone formation or grafting materials including biologics should be used at the surgeon’s discretion; however, use of biologics should be limited to FDA approved indications in order to limit complications (especially BMP).
    • All operative interventions must be based upon positive correlation of clinical findings, clinical course, and diagnostic tests and must be performed by surgeons with appropriate training (neurosurgery, orthopedic surgery). A comprehensive assimilation of these factors must lead to a specific diagnosis with positive identification of pathologic condition(s). A failure of accurate correlation may be an indication for denial of cases. It is imperative to rule out non-physiologic modifiers of pain presentation or non-operative conditions mimicking radiculopathy or instability (e.g., peripheral neuropathy, piriformis syndrome, myofascial pain, sympathetically mediated pain syndromes, sacroiliac dysfunction, psychological conditions, etc.) prior to consideration of elective surgical intervention. 
    • Operative treatment is indicated when the natural history of surgically treated lesions is better than the natural history for non-operatively treated lesions. 
      • All individuals being considered for surgical intervention should first undergo a comprehensive neuro-musculoskeletal examination to identify mechanical pain generators that may respond to non-surgical techniques or may be refractory to surgical intervention.
      • While sufficient time allowances for non-operative treatment are required to determine the natural cause and response to non-operative treatment of low back pain disorders, timely decision making for operative intervention is critical to avoid de-conditioning and increased disability (exclusive of "emergent" or urgent pathology such as cauda equina syndrome or associated rapidly progressive neurologic loss). 
• In general, if the program of non-operative treatment fails, operative treatment is indicated when: 
  • Improvement of the symptoms has plateaued or failed to occur, and the residual symptoms of pain and functional disability are unacceptable at the end of 6 to 12 weeks of active treatment, or at the end of longer duration of non-operative programs for debilitated individuals with complex problems; and/or 
  • Frequent recurrences of symptoms cause serious functional limitations even if a non-operative active treatment program provides satisfactory relief of symptoms, and restoration of function on each recurrence. 

References

1. Society NAS. Evidence-Based Clinical Guidelines for Multidisciplinary Spine Care Diagnosis and Treatment of Low Back Pain. North American Spine Society. May, 2023. Accessed May, 2023. https://www.spine.org/Portals/0/assets/downloads/ResearchClinicalCare/Guidelines/LowBackPain.pdf
2. Chou R, Baisden J, Carragee EJ, Resnick DK, Shaffer WO, Loeser JD. Surgery for low back pain: a review of the evidence for an American Pain Society Clinical Practice Guideline. Spine (Phila Pa 1976). May 1 2009;34(10):1094-109. doi:10.1097/BRS.0b013e3181a105fc
3. Kreiner DS, Hwang SW, Easa JE, et al. An evidence-based clinical guideline for the diagnosis and treatment of lumbar disc herniation with radiculopathy. Spine J. Jan 2014;14(1):180-91. doi:10.1016/j.spinee.2013.08.003
4. Tosteson AN, Tosteson TD, Lurie JD, et al. Comparative effectiveness evidence from the spine patient outcomes research trial: surgical versus nonoperative care for spinal stenosis, degenerative spondylolisthesis, and intervertebral disc herniation. Spine (Phila Pa 1976). Nov 15 2011;36(24):2061-8. doi:10.1097/BRS.0b013e318235457b
5. Qaseem A, Wilt TJ, McLean RM, et al. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. Apr 4 2017;166(7):514-530. doi:10.7326/m16-2367
6. Parker SL, Godil SS, Mendenhall SK, Zuckerman SL, Shau DN, McGirt MJ. Two-year comprehensive medical management of degenerative lumbar spine disease (lumbar spondylolisthesis, stenosis, or disc herniation): a value analysis of cost, pain, disability, and quality of life: clinical article. J Neurosurg Spine. Aug 2014;21(2):143-9. doi:10.3171/2014.3.Spine1320
7. Delgado-López PD, Rodríguez-Salazar A, Martín-Alonso J, Martín-Velasco V. [Lumbar disc herniation: Natural history, role of physical examination, timing of surgery, treatment options and conflicts of interests]. Neurocirugia (Astur). May-Jun 2017;28(3):124-134. Hernia discal lumbar: historia natural, papel de la exploración, timing de la cirugía, opciones de tratamiento y conflicto de intereses. doi:10.1016/j.neucir.2016.11.004
8. Delitto A, Piva SR, Moore CG, et al. Surgery versus nonsurgical treatment of lumbar spinal stenosis: a randomized trial. Ann Intern Med. Apr 7 2015;162(7):465-73. doi:10.7326/m14-1420
9. Fardon DF, Williams AL, Dohring EJ, Murtagh FR, Gabriel Rothman SL, Sze GK. Lumbar disc nomenclature: version 2.0: Recommendations of the combined task forces of the North American Spine Society, the American Society of Spine Radiology and the American Society of Neuroradiology. Spine J. Nov 1 2014;14(11):2525-45. doi:10.1016/j.spinee.2014.04.022
10. Li Y, Fredrickson V, Resnick DK. How should we grade lumbar disc herniation and nerve root compression? A systematic review. Clin Orthop Relat Res. Jun 2015;473(6):1896-902. doi:10.1007/s11999-014-3674-y
11. Atlas SJ, Keller RB, Wu YA, Deyo RA, Singer DE. Long-term outcomes of surgical and nonsurgical management of lumbar spinal stenosis: 8 to 10 year results from the maine lumbar spine study. Spine (Phila Pa 1976). Apr 15 2005;30(8):936-43. doi:10.1097/01.brs.0000158953.57966.c0
12. Tosteson AN, Lurie JD, Tosteson TD, et al. Surgical treatment of spinal stenosis with and without degenerative spondylolisthesis: cost-effectiveness after 2 years. Ann Intern Med. Dec 16 2008;149(12):845-53. doi:10.7326/0003-4819-149-12-200812160-00003
13. Weinstein JN, Lurie JD, Tosteson TD, et al. Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesis. N Engl J Med. May 31 2007;356(22):2257-70. doi:10.1056/NEJMoa070302
14. Katz JN, Zimmerman ZE, Mass H, Makhni MC. Diagnosis and Management of Lumbar Spinal Stenosis: A Review. Jama. May 3 2022;327(17):1688-1699. doi:10.1001/jama.2022.5921
15. Eck JC, Sharan A, Ghogawala Z, et al. Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 7: lumbar fusion for intractable low-back pain without stenosis or spondylolisthesis. J Neurosurg Spine. Jul 2014;21(1):42-7. doi:10.3171/2014.4.Spine14270
16. Fritzell P, Hägg O, Wessberg P, Nordwall A. 2001 Volvo Award Winner in Clinical Studies: Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group. Spine (Phila Pa 1976). Dec 1 2001;26(23):2521-32; discussion 2532-4.  doi:10.1097/00007632-200112010-00002
17. Mannion AF, Brox JI, Fairbank JC. Consensus at last! Long-term results of all randomized controlled trials show that fusion is no better than non-operative care in improving pain and disability in chronic low back pain. Spine J. May 2016;16(5):588-90. doi:10.1016/j.spinee.2015.12.001
18. Matz PG, Meagher RJ, Lamer T, et al. Guideline summary review: An evidence-based clinical guideline for the diagnosis and treatment of degenerative lumbar spondylolisthesis. Spine J. Mar 2016;16(3):439-48. doi:10.1016/j.spinee.2015.11.055
19. Matz PG, Meagher RJ, Lamer T, et al. Evidence-Based Clinical Guidelines for Multidisciplinary Spine Care: Diagnosis and Treatment of Degenerative Lumar Spondylolisthesis. North American Spine Society (NASS). Updated 2014. Accessed February 8, 2022.  https://www.spine.org/Portals/0/assets/downloads/ResearchClinicalCare/Guidelines/Spondylolisthesis.pdf
20. Abdu WA, Sacks OA, Tosteson ANA, et al. Long-Term Results of Surgery Compared With Nonoperative Treatment for Lumbar Degenerative Spondylolisthesis in the Spine Patient Outcomes Research Trial (SPORT). Spine (Phila Pa 1976). Dec 1 2018;43(23):1619-1630. doi:10.1097/brs.0000000000002682
21. Gonzalez GA, Porto G, Hines K, et al. Clinical Outcomes with and without Adherence to Evidence-Based Medicine Guidelines for Lumbar Degenerative Spondylolisthesis Fusion Patients. J Clin Med. Feb 2 2023;12(3)doi:10.3390/jcm12031200
22. Phillips FM, Slosar PJ, Youssef JA, Andersson G, Papatheofanis F. Lumbar spine fusion for chronic low back pain due to degenerative disc disease: a systematic review. Spine (Phila Pa 1976). Apr 1 2013;38(7):E409-22. doi:10.1097/BRS.0b013e3182877f11
23. Yavin D, Casha S, Wiebe S, et al. Lumbar Fusion for Degenerative Disease: A Systematic Review and Meta-Analysis. Neurosurgery. May 1 2017;80(5):701-715. doi:10.1093/neuros/nyw162
24. Kang YN, Ho YW, Chu W, Chou WS, Cheng SH. Effects and Safety of Lumbar Fusion Techniques in Lumbar Spondylolisthesis: A Network Meta-Analysis of Randomized Controlled Trials. Global Spine J. Apr 2022;12(3):493-502. doi:10.1177/2192568221997804
25. Gadjradj PS, Basilious M, Goldberg JL, et al. Decompression alone versus decompression with fusion in patients with lumbar spinal stenosis with degenerative spondylolisthesis: a systematic review and meta-analysis. Eur Spine J. Mar 2023;32(3):1054-1067. doi:10.1007/s00586-022-07507-1
26. Truumees E, Prather H. Orthopaedic Knowledge Update: Spine 6 Academy of Orthopaedic Surgeions; 2021:608.
27. Deyo RA, Mirza SK, Martin BI, Kreuter W, Goodman DC, Jarvik JG. Trends, major medical complications, and charges associated with surgery for lumbar spinal stenosis in older adults. Jama. Apr 7 2010;303(13):1259-65. doi:10.1001/jama.2010.338
28. Endler P, Ekman P, Möller H, Gerdhem P. Outcomes of Posterolateral Fusion with and without Instrumentation and of Interbody Fusion for Isthmic Spondylolisthesis: A Prospective Study. J Bone Joint Surg Am. May 3 2017;99(9):743-752. doi:10.2106/jbjs.16.00679
29. Said E, Abdel-Wanis ME, Ameen M, et al. Posterolateral Fusion Versus Posterior Lumbar Interbody Fusion: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Global Spine J. Jun 2022;12(5):990-1002. doi:10.1177/21925682211016426
30. Puvanesarajah V, Shen FH, Cancienne JM, et al. Risk factors for revision surgery following primary adult spinal deformity surgery in patients 65 years and older. J Neurosurg Spine. Oct 2016;25(4):486-493. doi:10.3171/2016.2.Spine151345
31. Alvarez Reyes A, Jack AS, Hurlbert RJ, Ramey WL. Complications in the Elderly Population Undergoing Spinal Deformity Surgery: A Systematic Review and Meta-Analysis. Global Spine J. Oct 2022;12(8):1934-1942. doi:10.1177/21925682221078251
32. Patel RA, Wilson RF, Patel PA, Palmer RM. The effect of smoking on bone healing: A systematic review. Bone Joint Res. 2013;2(6):102-11. doi:10.1302/2046-3758.26.2000142
33. Andersen T, Christensen FB, Laursen M, Høy K, Hansen ES, Bünger C. Smoking as a predictor of negative outcome in lumbar spinal fusion. Spine (Phila Pa 1976). Dec 1 2001;26(23):2623-8. doi:10.1097/00007632-200112010-00018
34. Glassman SD, Anagnost SC, Parker A, Burke D, Johnson JR, Dimar JR. The effect of cigarette smoking and smoking cessation on spinal fusion. Spine (Phila Pa 1976). Oct 15 2000;25(20):2608-15. doi:10.1097/00007632-200010150-00011
35. Jackson KL, 2nd, Devine JG. The Effects of Smoking and Smoking Cessation on Spine Surgery: A Systematic Review of the Literature. Global Spine J. Nov 2016;6(7):695-701. doi:10.1055/s-0036-1571285
36. Khalid SI, Thomson KB, Chilakapati S, et al. The Impact of Smoking Cessation Therapy on Lumbar Fusion Outcomes. World Neurosurg. Aug 2022;164:e119-e126. doi:10.1016/j.wneu.2022.04.031
37. Nunna RS, Ostrov PB, Ansari D, et al. The Risk of Nonunion in Smokers Revisited: A Systematic Review and Meta-Analysis. Global Spine J. Apr 2022;12(3):526-539. doi:10.1177/21925682211046899
38. Alsoof D, Johnson K, McDonald CL, Daniels AH, Cohen EM. Body Mass Index and Risk of Complications After Posterior Lumbar Spine Fusion: A Matched Cohort Analysis Investigating Underweight and Obese Patients. J Am Acad Orthop Surg. Apr 1 2023;31(7):e394-e402. doi:10.5435/jaaos-d-22-00667

Coding Section

Procedure and diagnosis codes on Medical Policy documents are included only as a general reference tool for each policy. They may not be all-inclusive. 

This medical policy was developed through consideration of peer-reviewed medical literature generally recognized by the relevant medical community, U.S. FDA approval status, nationally accepted standards of medical practice and accepted standards of medical practice in this community, Blue Cross Blue Shield Association technology assessment program (TEC) and other nonaffiliated technology evaluation centers, reference to federal regulations, other plan medical policies, and accredited national guidelines.

"Current Procedural Terminology © American Medical Association. All Rights Reserved" 

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